Cheese Tortellini Pepperoni Pizza Casserole-A cheesy, saucy, pepperoni-packed casserole that fuses the best of pizza and pasta—perfect for busy weeknights or weekend comfort food cravings.

Introduction

If you’ve ever found yourself torn between pizza and pasta for dinner, this Cheese Tortellini Pepperoni Pizza Casserole is your delicious solution. It’s a one-dish wonder that combines pillowy cheese tortellini, zesty pizza sauce, crispy pepperoni, and a gooey blanket of melted mozzarella—all baked to golden perfection.

This casserole is a hit with kids and adults alike. It’s quick to prepare, easy to customize, and makes enough to feed a hungry crowd. Whether you’re hosting a casual dinner, prepping for game night, or just want something indulgent and satisfying, this dish delivers big flavor with minimal effort.

Ingredients

1 package (9 oz) cheese tortellini (fresh or frozen)
1 jar (24 oz) pizza sauce
1 cup sliced pepperoni
2 cups shredded mozzarella cheese
1 cup shredded Italian cheese blend (optional)
1 teaspoon Italian seasoning
½ teaspoon garlic powder
¼ teaspoon red pepper flakes (optional, for heat)
Fresh basil or parsley, for garnish

Instructions

Step 1: Preheat the Oven

Preheat your oven to 375°F (190°C). Grease a 9×13-inch baking dish with cooking spray or olive oil.

Step 2: Cook the Tortellini

Cook the tortellini according to package instructions. Drain and set aside. If using frozen tortellini, make sure it’s fully thawed and cooked before assembling the casserole.

Step 3: Mix the Filling

In a large bowl, combine the cooked tortellini, pizza sauce, half of the mozzarella cheese, pepperoni slices, Italian seasoning, garlic powder, and red pepper flakes. Stir until everything is evenly coated and well mixed.

Step 4: Assemble the Casserole

Transfer the mixture to the prepared baking dish. Spread it out evenly. Top with the remaining mozzarella and the optional Italian cheese blend for extra gooeyness.

Step 5: Bake

Cover the dish with foil and bake for 20 minutes. Remove the foil and bake for an additional 10–15 minutes, or until the cheese is bubbly and golden brown.

Step 6: Garnish and Serve

Let the casserole cool slightly. Garnish with fresh basil or parsley for a pop of color and freshness. Serve warm and enjoy!

Serving Suggestions

Serve with garlic bread or breadsticks for dipping
Add a side salad with Italian dressing for balance
Pair with sparkling water, iced tea, or red wine
Offer extra toppings like olives, mushrooms, or jalapeños on the side

Tips & Variations

Make it vegetarian: Skip the pepperoni and add sautéed mushrooms, bell peppers, or spinach
Add protein: Mix in cooked sausage, ground beef, or shredded chicken
Use different sauces: Try marinara, vodka sauce, or Alfredo for a twist
Make it ahead: Assemble the casserole up to 24 hours in advance and refrigerate until ready to bake
Freeze leftovers: Store in airtight containers and freeze for up to 2 months. Reheat in the oven or microwave

Storage & Reheating

Refrigerate leftovers for up to 4 days
Reheat individual portions in the microwave or oven until warmed through
Freeze in portions for easy weeknight meals—thaw overnight and bake until bubbly

Final Thoughts

This Cheese Tortellini Pepperoni Pizza Casserole is everything you love about pizza night—without the dough. It’s cheesy, saucy, and packed with flavor, making it a guaranteed hit for family dinners, potlucks, or cozy nights in. With simple ingredients and endless customization options, it’s a recipe you’ll come back to again and again.